A simplified purification protocol for recombinant adeno-associated virus vectors
نویسندگان
چکیده
منابع مشابه
A simplified purification protocol for recombinant adeno-associated virus vectors
We describe a new rapid, low cost, and scalable method for purification of various recombinant adeno-associated viruses (rAAVs) from the lysates of producer cells of either mammalian or insect origin. The method takes advantage of two general biochemical properties of all characterized AAV serotypes: (i) low isoelectric point of a capsid and (ii) relative biological stability of the viral parti...
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ژورنال
عنوان ژورنال: Molecular Therapy - Methods & Clinical Development
سال: 2014
ISSN: 2329-0501
DOI: 10.1038/mtm.2014.34